🗺️ Biotech & Pharma · Journey Playbooks

Playbook: Deliver an NGS analysis package

QC-passed, versioned, inspection-ready sequencing results with provenance.

journey~120 minBioinformaticiansLab ScientistsRegulatory Affairs

Journey Steps

1Step 1 — Quality-control sequencing data before analysis: start with "Run read-level QC: per-base quality, GC bias, duplication profiles"
2Step 2 — Standardize variant calling and annotation: start with "Fix caller versions and filter thresholds in writing before processing"
3Step 3 — Version protocols like software: start with "Store protocols in controlled repo with semver-style versions"
4How it fits together: Reference builds and tool versions recorded everywhere. Future-you and auditors both say thanks.

Commands

Install all referenced skills

$ npx skills add aniruddhaadak80/skills --skill bioinformatics-seq-qc-pipeline && npx skills add aniruddhaadak80/skills --skill bioinformatics-variant-calling-sop && npx skills add aniruddhaadak80/skills --skill lab-informatics-protocol-versioning

Tags

#playbook#journey#biotech-pharma

Install this skill

$ npx skills add aniruddhaadak80/skills --skill playbook-biotech-pharma-ngs-analysis -a opencode

SKILL.md

# Playbook: Deliver an NGS analysis package

> QC-passed, versioned, inspection-ready sequencing results with provenance.

## When to Use This Skill

QC-passed, versioned, inspection-ready sequencing results with provenance.

## Steps

1. Step 1 — Quality-control sequencing data before analysis: start with "Run read-level QC: per-base quality, GC bias, duplication profiles"
2. Step 2 — Standardize variant calling and annotation: start with "Fix caller versions and filter thresholds in writing before processing"
3. Step 3 — Version protocols like software: start with "Store protocols in controlled repo with semver-style versions"
4. How it fits together: Reference builds and tool versions recorded everywhere. Future-you and auditors both say thanks.

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